Publications

Journal Article

Synthesis and Exploitation of the Biological Profile of Novel Guanidino Xylofuranose Derivatives
CHEMMEDCHEM, 17, 2022
Andreia Fortuna , Rita Goncalves-Pereira , Paulo J. Costa , Radek Jorda , Veronika Vojackova , Gabriel Gonzalez , V Heise , Rene Csuk , M. Conceição Oliveira , Nuno Manuel Xavier

Special Issue "Carbohydrates 2018"
PHARMACEUTICALS, 13, 2020
Amélia P. Rauter , Nuno Manuel Xavier

Synthesis of Triazole-Containing Furanosyl Nucleoside Analogues and Their Phosphate, Phosphoramidate or Phoshonate Derivatives as Potential Sugar Diphosphate or Nucleotide Mimetics
CHEMPLUSCHEM, 85, 1676-1691 8 2020
Andreia Fortuna , Paulo J. Costa , M.Fatima M.Piedade , M. Conceição Oliveira , Nuno Manuel Xavier

Novel dodecyl-containing azido and glucuronamide-based nucleosides exhibiting anticancer potential
PURE AND APPLIED CHEMISTRY, 91, 1085–1105 2019
Nuno Manuel Xavier , Rita Goncalves-Pereira , Radek Jorda , Denisa Hendrychová , M. Conceição Oliveira

Synthesis and biological evaluation of structurally varied 5´-/6´-isonucleosides and theobromine-containing N-isonucleosidyl derivatives
PHARMACEUTICALS, 12, 103 2019
Nuno Manuel Xavier , Eduardo C. de Sousa , Margarida P. Pereira , Anne Loesche , Immo Serbian , Rene Csuk , M. Conceição Oliveira

Sugar-based bactericides targeting phosphatidylethanolamine-enriched membranes
NATURE COMMUNICATIONS, 9, 11 2018
Catarina Dias , Joao P. Pais , Rafael Nunes , Maria-Teresa Blazquez-Sanchez , J. M. T. Marquês , Andreia F. Almeida , Patricia Serra , Nuno Manuel Xavier , Diogo Vila-Vicosa , Miguel Machuqueiro , A. Viana , Alice Martins , M. Soledade C. S. Santos , Ana Pelerito , Ricardo Dias , Rogerio Tenreiro , M. Conceição Oliveira , Marialessandra Contino , Nicola A. Colabufo , R. F. M. de Almeida , Amélia P. Rauter

Furanosyl Nucleoside Analogues Embodying Triazole or Theobromine Units as Potential Lead Molecules for Alzheimer s Disease
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, , 2667-2681 6 2018
Rita Goncalves-Pereira , Margarida P. Pereira , Sofia G. Serra , Anne Loesche , Rene Csuk , Samuel Silvestre , Paulo J. Costa , M. Conceição Oliveira , Nuno Manuel Xavier

Exploitation of new structurally diverse D-glucuronamide-containing N-glycosyl compounds: synthesis and anticancer potential
ORGANIC & BIOMOLECULAR CHEMISTRY, 15, 4667-4680 6 2017
Nuno Manuel Xavier , Alexandre Porcheron , Daniela Batista , Radek Jorda , Eva Reznickova , Vladimir Krystof , M. Conceição Oliveira

Synthesis and antiproliferative evaluation of novel azido nucleosides and their phosphoramidate derivatives
PURE AND APPLIED CHEMISTRY, 89, 1267-1281 9 2017
Nuno Manuel Xavier , Rita Goncalves-Pereira , Radek Jorda , Eva Reznickova , Vladimir Krystof , M. Conceição Oliveira

Synthesis of 1,5-Anhydro-D-glycero-D-gluco-heptitol Derivatives as Potential Inhibitors of Bacterial Heptose Biosynthetic Pathways
SYNTHESIS-STUTTGART, 49, 5320-5334 12 2017
Markus Blaukopf , Dmytro Atamanyuk , Nuno Manuel Xavier , Vincent Gerusz , Paul Kosma

Liquid crystalline glycosteroids and acyl steroid glycosides (ASG)
LIQUID CRYSTALS, 44, 2089-2107 2017
Zonglong Yang , Rui Xu , Fahima Ali-Rachedi , Stephane Chambert , Nuno Manuel Xavier , Laurent Soulere , Mohammed Ahmar , Grahame Mackenzie , Edward J. Davis , John W. Goodby , Stephen J. Cowling , Yves Queneau

Synthesis of glucopyranos-6 -yl purine and pyrimidine isonucleosides as potential cholinesterase inhibitors. Access to pyrimidine-linked pseudodisaccharides through Mitsunobu reaction
PURE AND APPLIED CHEMISTRY, 88, 363-379 4 2016
Daniela Batista , Stefan Schwarz , Anne Loesche , Rene Csuk , Paulo J. Costa , M. Conceição Oliveira , Nuno Manuel Xavier

Synthesis and Evaluation of the Biological Profile of Novel Analogues of Nucleosides and of Potential Mimetics of Sugar Phosphates and Nucleotides
SYNLETT, 26, 2663-2672 12 2015
Nuno Manuel Xavier , Susana D. Lucas , Radek Jorda , Stefan Schwarz , Anne Loesche , Rene Csuk , M. Conceição Oliveira

Self-organizing behaviour of glycosteroidal bolaphiles: insights into lipidic microsegregation
ORGANIC \& BIOMOLECULAR CHEMISTRY, 13, 783-792 2015
R. Xu , F. Ali-Rachedi , Nuno Manuel Xavier , S. Chambert , F. Ferkous , Y. Queneau , S. J. Cowling , E. J. Davis , J. W. Goodby

A natural approach: Synthesis and cytoxicity of monodesmosidic glycyrrhetinic acid glycosides
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 72, 78-83 1 2014
Stefan Schwarz , Bianka Siewert , Nuno Manuel Xavier , Ana R. Jesus , Amélia P. Rauter , Rene Csuk

Synthesis of Purine Nucleosides from D- Glucuronic Acid Derivatives and Evaluation of Their Cholinesterase- Inhibitory Activities
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2014, 2770-2779 5 2014
Nuno Manuel Xavier , Stefan Schwarz , P. D. Vaz , Rene Csuk , Amélia P. Rauter

Enantioselective Synthesis in Carbohydrate-Based Drug Discovery: Imino Sugars, Alkaloids and Macrolide Antibiotics
CURRENT TOPICS IN MEDICINAL CHEMISTRY, 14, 1235-1243 2014
Nuno Manuel Xavier , Amélia P. Rauter

Efficient and First Regio- and Stereoselective Direct C-Glycosylation of a Flavanone Catalysed by Pr(OTf)(3) Under Conventional Heating or Ultrasound Irradiation
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, , 1441-1447 3 2013
Rui G. Santos , Nuno Manuel Xavier , Joao C. Bordado , Amélia P. Rauter

Environmentally friendly approaches to the synthesis of new antibiotics from sugars
PURE AND APPLIED CHEMISTRY, 84, 803-816 2012
Nuno Manuel Xavier , Amélia P. Rauter

Exploitation of Furanoid 5-Azido-3-C-Branched-Chain Sugars Towards Highly Functionalized Nitrogen-Containing Carbohydrate Derivatives
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, , 713-720 2 2011
Nuno Manuel Xavier , Y. Queneau , Amélia P. Rauter

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